Effective electrophoretic mobilities and charges of anti-VEGF proteins determined by capillary zone electrophoresis
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چکیده
منابع مشابه
Determination of absolute mobilities, pK values and separation numbers by capillary zone electrophoresis: effective mobility as a parameter for screening
Migration times or apparent mobilities can never be used for the identification of ionic species in capillary zone electrophoresis if an electroosmotic flow (EOF) is present, because the velocity of this flow varies considerably with the “state” of the capillary. From the migration times of the EOF and the ionic species, the effective mobilities can be calculated. These effective mobilities are...
متن کاملStudy of the Electrophoretic Behavior of Cephalosporins by Capillary Zone Electrophoresis.
PURPOSE The aim of the study was the characterization of the electrophoretic behavior of cephalosporins from different generation having different structural characteristics in order to develop a rapid, simple and efficient capillary electrophoretic method for their identification and simultaneous separation from complex mixtures. METHODS Ten cephalosporin derivatives (cefaclor, cefadroxil, c...
متن کاملDetermination of Varenicline by Capillary Zone Electrophoresis
HASSAN A ALHAZMI, HAFIZ A MAKEEN, SAMI EL DEEB Department of Pharmaceutical Chemistry, College of pharmacy, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia. Department of Clinical Pharmacy, College of pharmacy, Jazan University, P.O. Box 114, Jazan 45142, Saudi Arabia. Institute of Pharmacy, Freie Universität Berlin, Berlin, Germany Department of Pharmaceutical Chemistry, Al-Azhar Uni...
متن کاملApplication of the Phenomenological Model to Electrophoretic Mobility in Mixed Solvent Electrolyte Systems in Capillary Zone Electrophoresis
The phenomenological model of Khossravi and Connors (1992) has been adopted to calculate the electrophoretic mobility of drugs at different concentrations of solvents in a binary mixture. The accuracy and predictability of the model have been evaluated employing 14 experimental data sets by using average percentage mean deviation (APMD). The obtained APMD for correlative and predictive studies ...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical and Biomedical Analysis
سال: 2011
ISSN: 0731-7085
DOI: 10.1016/j.jpba.2010.12.027